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September 1, 1998Pacing and Clinical Electrophysiology

Prevention of Atrial Arrhythmias during DDD Pacing by Atrial Overdrive

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Why the study?

Does atrial overdrive pacing reduce the incidence and burden of atrial arrhythmias in patients with DDD pacemakers?

Population

22 patients with Chorus 6234 DDD pacemakers, mean age 67 +/- 9 years, 7 women and 15 men.

Comparison

Atrial overdrive for 1 month. vs Baseline pacing with lower rate programmed to 55…

Design

Cohort

Follow-up

3 months (three phases of 1 month each)

Authors

Stéphane Garrigue
Stéphane GarrigueElectrophysiology
SBS. SERG BAROLDUniversity of Rochester
Serge Cazeau
Serge CazeauElectrophysiology

Discussion

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Overview

May reduce AA burden with atrial overdrive in DDD pacemakers; leaves open need for randomized confirmation.

Structured PICO

Does atrial overdrive pacing reduce the incidence and burden of atrial arrhythmias in patients with DDD pacemakers?

P
Population
22 patients with Chorus 6234 DDD pacemakers, mean age 67 +/- 9 years, 7 women and 15 men.
I
Intervention
Atrial overdrive (programmed paced rate 10 ppm faster than the mean ventricular rate stored for the last 24-hour period in the pacemaker memory) for 1 month.
C
Comparator
Baseline pacing with lower rate programmed to 55 ppm for 1 month.
O
Outcome
Incidence of atrial arrhythmias (AA), number and maximal duration of AA episodes, and total AA time in a month.surrogate

Atrial overdrive pacing significantly reduces the incidence and burden of atrial arrhythmias in patients with DDD pacemakers over a short-term period.

Limitations

  • Short-term data

Cite This Study

Garrigue et al. (1998) studied this question.

synapsesocial.com/papers/6a7e6ae9567bd3ec6fb7b4fbhttps://doi.org/10.1111/j.1540-8159.1998.tb00275.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A New Pacing Algorithm for Overdrive Suppression of Atrial Fibrillation1994 · 117 citations
  2. 2DDD Pacing: An Effective Treatment Modality for Recurrent Atrial Arrhythmias1988 · 108 citations
  3. 3Reliability of a New Algorithm for Automatic Mode Switching from DDDR to DDIR Pacing Mode in Sinus Node Disease Patients with Chronotropic Incompetence and Recurrent Paroxysmal Atrial Fibrillation1996 · 26 citations
  4. 4Long‐term Prevention of Vagal Atrial Arrhythmias by Atrial Pacing at 90/Minute: Experience with 6 Cases1983 · 122 citations
  5. 5Effect of Varying Atrial Sensitivity, AV Interval, and Detection Algorithm on Automatic Mode Switching1996 · 29 citations