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January 1, 2007Hypertension ResearchOpen Access

Masked Nocturnal Hypertension and Target Organ Damage in Hypertensives with Well-Controlled Self-Measured Home Blood Pressure

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Why the study?

Does masked nocturnal hypertension increase target organ damage in subjects with well-controlled self-measured home blood pressure?

Population

165 community-dwelling subjects with well-controlled self-measured home blood pressure (<135/85 mmHg)

Comparison

Masked nocturnal hypertension vs Normotensive

Design

Cross-sectional

Authors

SHSatoshi HoshidePreventive CardiologyJIJoji IshikawaTokyo Metropolitan Institute of GerontologyTOToshiyuki OjimaHamamatsu University

Discussion

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Implication

Masked nocturnal hypertension may signal higher target organ damage risk despite controlled home BP; leaves open value of ambulatory monitoring.

Structured PICO

Does masked nocturnal hypertension increase target organ damage in subjects with well-controlled self-measured home blood pressure?

P
Population
165 community-dwelling subjects with well-controlled self-measured home blood pressure (<135/85 mmHg)
I
Intervention
Masked nocturnal hypertension (ambulatory nocturnal BP ≥120/75 mmHg)
C
Comparator
Normotensive (ambulatory nocturnal BP <120/75 mmHg)
O
Outcome
Target organ damage assessed by intima-media thickness (IMT) and relative wall thickness (RWT)surrogate

Masked nocturnal hypertension is associated with increased target organ damage (greater IMT and RWT) even in patients with well-controlled home blood pressure, highlighting the potential need for ambulatory BP monitoring.

Cite This Study

Hoshide et al. (2007) studied this question.

synapsesocial.com/papers/6a7e6b42567bd3ec6fb7b519https://doi.org/10.1291/hypres.30.143

Topics

Hypertension management
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Also Consider

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  1. 1Ambulatory blood pressure. An independent predictor of prognosis in essential hypertension.1994 · 1,682 citations
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  4. 4Prevalence and Clinical Significance of Isolated Ambulatory Hypertension in Young Subjects Screened for Stage 1 Hypertension2004 · 82 citations
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