Why the study?
Do normal-weight women with PCOS have altered insulin sensitivity, secretion, or glucose effectiveness compared to matched controls?
Population
40 normal-weight women
Design
Case-control
Authors
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May reflect early metabolic alteration in normal-weight PCOS; leaves open whether glucose effectiveness predicts future diabetes.
Do normal-weight women with PCOS have altered insulin sensitivity, secretion, or glucose effectiveness compared to matched controls?
Normal-weight women with PCOS have preserved insulin sensitivity and secretion but exhibit decreased glucose effectiveness and increased total body fat compared to matched controls.
Gennarelli et al. (2005) studied this question.
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