Why the study?
Does high-dose α-lipoic acid improve heart rate variability in type 2 diabetes mellitus patients with cardiac autonomic neuropathy?
Population
75 patients with Type 2 Diabetes Mellitus and Cardiac Autonomic Neuropathy in Korea
Comparison
α-lipoic acid oral dose of 600 mg/day for the… vs Placebo treatment for 24 weeks
Design
RCT, randomly assigned, double-blind, placebo-controlled
Follow-up
24 weeks
Authors
Loading...
High-dose α-lipoic acid does not improve heart rate variability in type 2 diabetes with cardiac autonomic neuropathy; challenges its therapeutic role and directs research to alternatives.
Does high-dose α-lipoic acid improve heart rate variability in type 2 diabetes mellitus patients with cardiac autonomic neuropathy?
High-dose α-lipoic acid for 24 weeks was well-tolerated but did not significantly improve heart rate variability in patients with type 2 diabetes and cardiac autonomic neuropathy.
Lee et al. (2017) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: