Why the study?
Does mass rotavirus vaccination reduce healthcare utilization for diarrhea in US children under 5 years of age?
Does mass rotavirus vaccination reduce healthcare utilization for diarrhea in US children under 5 years of age?
Mass rotavirus vaccination significantly reduces hospitalizations and healthcare costs for diarrheal disease in US children under 5 years of age.
Supports rotavirus vaccination in reducing US pediatric diarrhea hospitalizations; extends observational evidence while leaving causal effects open to randomized confirmation.
Evaluation of: Cortes JE, Curns AT, Tate JE et al. Rotavirus vaccine and health care utilization for diarrhea in U.S. children. N. Engl. J. Med. 365(12), 1108–1117 (2011). Cortes et al. thoroughly analyzed the effect of the introduction of mass rotavirus vaccination on healthcare utilization in a population of approximately 2 million US children under 5 years of age. According to the results of the study, hospitalization has been reduced from prevaccination periods by 89% for rotavirus diarrhea and by 44% for diarrheal disease. The estimated reduction of hospitalizations during the two (single-year) periods amounted to 64,855 and the respective savings in treatment costs were US$278 million. The significance of this paper is its approach to the estimation of vaccine efficacy by the assessment of vaccination coverage and hospitalization, as well as emergency department and outpatient visits in a large population of children without any ‘selection’ (e.g., hospitalization) bias.
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Martha M. Eibl (2012) studied this question.
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