Population
Mouse extensor digitorum longus muscles in vitro at 25 degrees C
Comparison
5-Hz, 20-s conditioning stimulus to increase… vs Baseline/unconditioned state
Design
Preclinical
Authors
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Cautions against clinical translation from rodent data; extends mechanistic insight into myosin phosphorylation but leaves relevance open.
Myosin regulatory light chain phosphorylation enhances muscle shortening, peak work, and power in mouse fast muscle, suggesting a functional role in movement.
Grange et al. (1995) studied this question.
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