Why the study?
Does aerobic exercise training alter the inflammatory and metabolic gene expression profile of epicardial and visceral adipose tissues in a pig model of familial hypercholesterolemia with CAD?
Population
Castrate male pig model of familial hypercholesterolemia with coronary atherosclerosis (CAD)
Comparison
Aerobic exercise training for 16 weeks vs Sedentary pigs matched for body weight
Design
Preclinical
Follow-up
16 weeks
Authors
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Supports heterogeneous adipose responses to exercise in CAD models; hypothesis-generating and should not yet influence clinical decisions.
Does aerobic exercise training alter the inflammatory and metabolic gene expression profile of epicardial and visceral adipose tissues in a pig model of familial hypercholesterolemia with CAD?
Aerobic exercise training elicits heterogeneous inflammatory and metabolic gene expression responses across different adipose tissue depots in a porcine model of coronary atherosclerosis.
Booth et al. (2010) studied this question.
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