Population
40 patients who underwent open heart surgery with extracorporeal circulation (ECC)
Design
Cohort
Follow-up
up to 8 days
Authors
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Associated hemostatic defects after extracorporeal circulation support careful monitoring in cardiac surgery; leaves optimal reversal strategies open to trials.
Open heart surgery with extracorporeal circulation induces significant quantitative and qualitative platelet defects and coagulation factor depletion, requiring careful heparin neutralization.
Moriau et al. (1977) studied this question.
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