Why the study?
Does acute blood pressure reduction reset the lower pressure limit of renal blood flow autoregulation in hypertensive rats?
Population
Two-kidney, one-clip hypertensive rats, spontaneously hypertensive rats, and normotensive Wistar-Kyoto rats
Comparison
Acute blood pressure reduction via removal of… vs Baseline and normotensive Wistar-Kyoto rats
Design
Preclinical
Follow-up
up to 30 minutes
Authors
Loading...
Does not support altering human BP targets; extends mechanistic insights on RBF autoregulation in hypertensive rat models.
Does acute blood pressure reduction reset the lower pressure limit of renal blood flow autoregulation in hypertensive rats?
Acute normalization of the pressure range of renal blood flow autoregulation in hypertensive rats depends on the degree of pressure reduction rather than renal innervation or plasma renin concentration.
Iversen et al. (1998) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: