Population
Rat kidney (cortex, outer medulla, and inner medulla), n=12
Comparison
Correction for endogenous L-arginine… vs Uncorrected measurement of NOS activity
Design
Preclinical
Authors
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Endogenous L-arginine correction is required for accurate renal NOS assays; hypothesis-generating in animal models with no immediate clinical implications.
Endogenous L-arginine levels vary across rat kidney regions and must be accounted for to accurately measure nitric oxide synthase activity.
Moridani et al. (1996) studied this question.
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