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January 1, 2021Fetal Diagnosis and Therapy

Prenatal Diagnosis of Aortic Coarctation: Prediction Algorithm according to Gestational Age

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Why the study?

To quantify the diagnostic accuracy of predictive anatomical factors of aortic coarctation and design a postnatal aortic coarctation probability algorithm based on gestational age in the prenatal period.

Does a gestational age-specific fetal echocardiography algorithm improve the prediction of postnatal aortic coarctation in fetuses with suspected CoA?

Population

114 fetuses with suspicion of CoA (2004-2020)

Design

Retrospective cohort study

Authors

LDLucía Deirós-BronteHospital Universitario La PazJDJesús Díez‐SebastiánHospital Universitario La PazRRR. RodríguezUniversity Hospital of Geneva

Discussion

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Implication

Should not yet change practice in suspected fetal CoA; leaves open prospective testing of GA-specific serial algorithms.

Structured PICO

Does a gestational age-specific fetal echocardiography algorithm improve the prediction of postnatal aortic coarctation in fetuses with suspected CoA?

P
Population
114 fetuses with suspicion of aortic coarctation (CoA) evaluated between 2004-2020
I
Intervention
Fetal echocardiography using gestational age-specific algorithms (isthmus-to-ductal ratio plus tricuspid/mitral valve ratio for ≤28 weeks, isthmus-to-ductal ratio plus isthmus z-scores for >28 weeks)
O
Outcome
Diagnostic accuracy for predicting postnatal aortic coarctationsurrogate

Gestational age-specific fetal echocardiography algorithms combining the isthmus-to-ductal ratio with other anatomical variables accurately predict postnatal aortic coarctation.

Cite This Study

Deirós-Bronte et al. (2021) studied this question.

synapsesocial.com/papers/6a7e9efaa390b11a0aa6c477https://doi.org/10.1159/000520449
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Ventricular discrepancy as a sonographic sign of coarctation of the fetal aorta: how reliable is it?1997 · 60 citations
  2. 2Normal fetal cardiac measurements derived by cross‐sectional echocardiography1992 · 148 citations
  3. 3Clinical implication of isolated right dominant heart in the fetus2007 · 24 citations
  4. 4Prenatal diagnosis of coarctation of the aorta improves survival and reduces morbidity: Table 12002 · 428 citations
  5. 5Importance of Relationship between Ductus and Isthmus in Fetal Diagnosis of Coarctation of Aorta2015 · 46 citations