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June 29, 2012Ultrasound in Obstetrics and Gynecology

Prediction of coarctation of the aorta in the second half of pregnancy

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Key result

A multiparametric scoring system yielded higher mean post-test probabilities in fetuses with confirmed coarctation of the aorta compared to normal fetuses (82% vs 55%, P=0.002 for ≤28 weeks).

Why the study?

Does a multiparametric fetal echocardiographic scoring system predict postnatal coarctation of the aorta in fetuses with cardiac asymmetry?

Population

85 appropriate-for-gestational age liveborn fetuses with isolated cardiac asymmetry prenatally diagnosed…

Design

Cohort

Follow-up

postnatal follow-up

Authors

EGEnery Gómez‐MontesResearch Institute Hospital 12 de OctubreIHIgnacio Herraı̀zUniversidad Complutense de MadridAMAlberto MendozaUniversity of California, Los Angeles

Discussion

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Implication

A multiparametric scoring system combining size-based fetal echocardiographic parameters and gestational age at diagnosis improves the prediction of postnatal coarctation of the aorta in fetuses with cardiac asymmetry.

Study Design

Type

Cohort (n=85)

Multicenter

No

Structured PICO

Does a multiparametric fetal echocardiographic scoring system predict postnatal coarctation of the aorta in fetuses with cardiac asymmetry?

P
Population
85 appropriate-for-gestational age liveborn fetuses with isolated cardiac asymmetry and complete postnatal follow-up, evaluated for postnatal coarctation of the aorta.
E
Exposure
Multiparametric scoring system combining gestational age at diagnosis, Z-score of ascending aorta diameter, pulmonary valve/aortic valve diameters ratio, and Z-score of aortic isthmus diameter.
O
Outcome
Postnatal confirmation of coarctation of the aorta (CoAo).surrogate

A multiparametric scoring system combining size-based fetal echocardiographic parameters and gestational age at diagnosis improves the prediction of postnatal coarctation of the aorta in fetuses with cardiac asymmetry.

Cite This Study

Gómez‐Montes et al. (2012) conducted a cohort in Fetuses with cardiac asymmetry (n=85). Multiparametric scoring system (cardiac parameters and gestational age) vs. Normal fetuses was evaluated on Postnatal coarctation of the aorta (CoAo). A multiparametric scoring system yielded higher mean post-test probabilities in fetuses with confirmed coarctation of the aorta compared to normal fetuses (82% vs 55%, P=0.002 for ≤28 weeks).

synapsesocial.com/papers/6a3fd68a901a52dbcb71b0fahttps://doi.org/10.1002/uog.11228

Topics

Echocardiography
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Ventricular discrepancy as a sonographic sign of coarctation of the fetal aorta: how reliable is it?1997 · 60 citations
  2. 2Coarctation of the aorta in prenatal life: an echocardiographic, anatomical, and functional study.1988 · 78 citations
  3. 3Normal fetal cardiac measurements derived by cross‐sectional echocardiography1992 · 148 citations
  4. 4Clinical implication of isolated right dominant heart in the fetus2007 · 24 citations
  5. 5Coarctation of the aorta from fetus to adult: curable condition or life long disease process?2005 · 175 citations