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November 27, 2015Medical Ultrasonography

The role of ventricular disproportion, aortic, and ductal isthmus ultrasound measurements for the diagnosis of fetal aortic coarctation, in the third trimester of pregnancy

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Why the study?

Do ventricular disproportion, aortic, and ductal isthmus ultrasound measurements predict the diagnosis of fetal aortic coarctation and the need for neonatal surgical intervention in fetuses with LV < RV disproportion?

Population

32 fetuses and newborns evaluated for left ventricle < right ventricle disproportion in the third trimester…

Design

Cohort

Follow-up

neonatal period

Authors

CMClaudiu MărgineanUniversitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu MureșCMCristina Oana MărgineanUniversitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu MureșIMIolanda MunteanUniversitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș

Discussion

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Member takes

Implication

LV-RV disproportion and isthmus measurements may aid fetal AoCo diagnosis; leaves open reliable prediction of neonatal surgery need.

Structured PICO

Do ventricular disproportion, aortic, and ductal isthmus ultrasound measurements predict the diagnosis of fetal aortic coarctation and the need for neonatal surgical intervention in fetuses with LV < RV disproportion?

P
Population
32 fetuses and newborns evaluated for left ventricle (LV) < right ventricle (RV) disproportion in the third trimester (pregnancy age 32 to 39 weeks, median 36 weeks). Fetuses with complex cardiac malformations were excluded.
I
Intervention
Ultrasound measurements of ventricular disproportion, aortic, and ductal isthmus (specifically RV/LV ratio, Ductus/Ao isthmus ratio, and Ao isthmus dimension)
O
Outcome
Diagnosis of fetal aortic coarctation (AoCo) and prediction of needed neonatal surgical interventionsurrogate

The combination of specific ultrasound measurements (RV/LV>1.5, Ductus/Ao isthmus >1.4, and Ao isthmus <4.2 mm) decreases false positive diagnosis of fetal aortic coarctation and helps predict the need for neonatal surgery.

Cite This Study

Mărginean et al. (2015) studied this question.

synapsesocial.com/papers/6a72f968bfabfe3aef60de3bhttps://doi.org/10.11152/mu.2013.2066.174.rvd
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prediction of coarctation of the aorta in the second half of pregnancy2012 · 80 citations
  2. 2Left Ventricular Strain, Arch Angulation, and Velocity-Time Integral Ratio Improve Performance of a Clinical Pathway for Fetal Diagnosis of Neonatal Coarctation of the Aorta2024 · 6 citations
  3. 3Utility of novel fetal echocardiographic morphometric measures of the aortic arch in the diagnosis of neonatal coarctation of the aorta2015 · 80 citations
  4. 4Prenatal Diagnosis of Aortic Coarctation: Prediction Algorithm according to Gestational Age2021 · 7 citations
  5. 5Fetal Echocardiographic Features for the Prediction of the Development of Aortic Coarctation in the Perinatal Period2026