Population
Mouse Leydig cells in vitro
Comparison
Synthetic atrial peptides vs Basal level and human chorionic gonadotropin (hCG)
Design
Preclinical
Authors
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Does not support clinical use; hypothesis-generating for natriuretic peptide effects on steroidogenesis, requiring in vivo and human validation.
Atrial natriuretic peptides stimulate testosterone production in mouse Leydig cells in vitro, suggesting a potential regulatory role in steroidogenesis.
Mukhopadhyay et al. (1986) studied this question.
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