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April 11, 2023EP EuropaceOpen Access

The positive predictive value for true atrial arrhythmia was 97.5% for all episodes ≥6 min, including 99.6% for episodes 1 h to <24 h and 100% for episodes ≥24 h.

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Why the study?

European AF guidelines recommend remote monitoring of device-detected AHREs and progression across pre-specified duration strata, but the capability of single-lead ICDs with an atrial sensing dipole to meet this recommendation required evaluation.

Does a single-lead ICD with an atrial sensing dipole accurately detect and remotely monitor atrial high-rate episodes in patients with a standard indication for a single-chamber ICD?

Population

1841 DX ICD patients with standard indication for single-chamber ICD from the MATRIX registry

Comparison

Remote monitoring of AHREs across pre-specified duration strata (6 min to <1 h, 1 h to <24 h, ≥24 h)

Design

Registry-based study

Authors

GHGerhard HindricksDTDominic A.M.J. TheunsDBD. Bar-Lev

Discussion

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Overview

May support remote AHRE monitoring with single-lead ICDs; leaves open effects on clinical outcomes.

Structured PICO

Does a single-lead ICD with an atrial sensing dipole accurately detect and remotely monitor atrial high-rate episodes in patients with a standard indication for a single-chamber ICD?

P
Population
1841 patients with standard indication for single-chamber ICD from the MATRIX registry, including a subgroup of 1451 patients with no history of atrial fibrillation.
I
Intervention
Single-lead implantable cardioverter-defibrillator (ICD) with an atrial sensing dipole (DX ICD system) utilizing daily automatic remote monitoring transmissions.
O
Outcome
Positive predictive values (PPVs) for device-detected atrial high-rate episodes (AHREs) to be true atrial arrhythmia across duration strata (6 min to <1 h, 1 h to <24 h, ≥ 24 h).surrogate

A single-lead ICD with an atrial sensing dipole provides highly accurate detection of atrial high-rate episodes, enabling reliable remote monitoring for subclinical atrial fibrillation.

Cite This Study

Hindricks et al. (2023) studied this question.

synapsesocial.com/papers/6a7eb4ea907a72384e8b9c37https://doi.org/10.1093/europace/euad061
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