Why the study?
Does strain imaging detect early left ventricular dysfunction in beta-thalassemia major patients without overt heart failure compared to healthy controls?
Population
32 patients with beta-thalassemia major without overt heart failure and 25 healthy controls
Comparison
Tissue velocity imaging and strain imaging vs Healthy controls
Design
Case-control
Authors
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Strain imaging may detect subclinical LV dysfunction in thalassemia with preserved LVEF; hypothesis-generating and requires prospective validation.
Does strain imaging detect early left ventricular dysfunction in beta-thalassemia major patients without overt heart failure compared to healthy controls?
Strain imaging and tissue velocity imaging can detect early regional left ventricular systolic dysfunction in beta-thalassemia major patients before overt heart failure or LVEF decline occurs.
Bilge et al. (2010) studied this question.
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