What question did this study set out to answer?

To evaluate the agreement between seated bioelectrical impedance analysis (BIA) and dual-energy X-ray absorptiometry (DXA) for measuring appendicular skeletal muscle mass and examine associations between phase angle and physical performance in older adults.

August 14, 2026SensorsOpen Access

Toward Clinically Feasible Assessment of Muscle Mass: Validation of a Seated Bioelectrical Impedance Device Against Dual-Energy X-Ray Absorptiometry (DXA) in Older Adults

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Authors

ÉPÉlodie PicheUniversité Côte d'Azur ÉMÉmeline MichelUniversité Côte d'Azur OGOlivier GuérinCentre National de la Recherche Scientifique

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Implication

Validation study demonstrates strong agreement between seated bioelectrical impedance and DXA in older adults, indicating a practical alternative for sarcopenia screening.

Key Points

To evaluate the agreement between seated bioelectrical impedance analysis (BIA) and dual-energy X-ray absorptiometry (DXA) for measuring appendicular skeletal muscle mass and examine associations between phase angle and physical performance in older adults.
Assessed 59 older adults (mean age 75 ± 7 years) who underwent DXA and seated BIA (Biody XpertZM3).
Estimated appendicular skeletal muscle mass (ASMM) using Kyle and Sergi equations and determined agreement using Lin's concordance correlation coefficient (CCC), Bland–Altman analysis, root mean square error (RMSE), and mean absolute error (MAE).
Evaluated correlations between phase angle (PhA), handgrip strength, and five-times sit-to-stand (5-STS) performance.
The Sergi equation showed superior concordance with DXA compared to the Kyle equation (CCC = 0.942 vs. 0.898; bias = 0.44 kg vs. 1.11 kg; RMSE = 1.33 kg vs. 1.96 kg).
Phase angle correlated positively with handgrip strength (r = 0.315, p = 0.015), but had no significant association with five-times sit-to-stand performance.

Cite This Study

Piche et al. (2026) studied this question.

synapsesocial.com/papers/6a7ec775b70b84ec8b913d77 https://doi.org/10.3390/s26165112

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Implication

Validation study demonstrates strong agreement between seated bioelectrical impedance and DXA in older adults, indicating a practical alternative for sarcopenia screening.

Toward Clinically Feasible Assessment of Muscle Mass: Validation of a Seated Bioelectrical Impedance Device Against Dual-Energy X-Ray Absorptiometry (DXA) in Older Adults

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Cite This Study

Toward Clinically Feasible Assessment of Muscle Mass: Validation of a Seated Bioelectrical Impedance Device Against Dual-Energy X-Ray Absorptiometry (DXA) in Older Adults

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Cite This Study

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