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First human evaluation of GP ablation effects on ventricular innervation; leaves open any arrhythmic risk or need to modify AF strategies.
The impact of ablation of ganglionated plexuses (GPs) during ablation of atrial fibrillation (AF) on ventricular myocardial innervation is unknown. Previous animal studies have shown different electrophysiological outcomes of ventricular myocardial denervation after ablation of autonomic ganglia.1,2 A recent animal report demonstrated that the ligament of Marshall could represent a conduit between the left stellate ganglion and the ventricle.2 There have been no reports evaluating detailed GP mapping and ablation in the atria and potential effects on ventricular sympathetic myocardial innervation.
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Lemery et al. (2016) studied this question.
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