December 26, 2012PLoS ONEOpen Access

Comparative Genomic Analysis of Coxsackievirus A6 Strains of Different Clinical Disease Entities

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Population

205 patients with coxsackievirus A6 infection treated at Chang Gung Memorial Hospital in 2009 and 2010…

Design

Cohort

Authors

YCYi‐Jen ChenCity Of Hope National Medical Center SCShih-Cheng ChangChang Gung University KTKuo‐Chien TsaoChang Gung University

Discussion

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Implication

Strain differences in coxsackievirus A6 may explain shifting clinical presentations; hypothesis-generating for genomic surveillance and prospective validation.

Structured PICO

Population

205 patients with coxsackievirus A6 (CVA6) infection treated at Chang Gung Memorial Hospital in 2009 and 2010, including 126 inpatients (62 in 2009, 64 in 2010)

Outcome

Clinical features and genomic sequence differences between 2009 and 2010 CVA6 isolates

Different genetic backgrounds of coxsackievirus A6 may lead to distinct clinical manifestations such as herpangina versus hand-foot-mouth disease.

Cite This Study

Chen et al. (2012) studied this question.

synapsesocial.com/papers/6a7ec8a32645279793b9962a https://doi.org/10.1371/journal.pone.0052432

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Implication

Strain differences in coxsackievirus A6 may explain shifting clinical presentations; hypothesis-generating for genomic surveillance and prospective validation.

Comparative Genomic Analysis of Coxsackievirus A6 Strains of Different Clinical Disease Entities

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Comparative Genomic Analysis of Coxsackievirus A6 Strains of Different Clinical Disease Entities

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider