Why the study?
Does combined administration of low dose heparin and aspirin prevent deep vein thrombosis in patients undergoing hip joint surgery?
Does combined administration of low dose heparin and aspirin prevent deep vein thrombosis in patients undergoing hip joint surgery?
Combined administration of low dose heparin and aspirin significantly reduces the incidence of deep vein thrombosis after hip joint surgery compared to aspirin alone or control.
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May support combined heparin-aspirin for post-hip DVT prevention; hypothesis-generating and requires RCT confirmation before practice change.
The study was carried out on 75 patients undergoing hip joint surgery. The efficacy of a prophylaxis of deep vein thrombosis (DVT) by acetylsalicyclic lysine (ASL) and by a low dose heparin (LDH) combined with the ASL treatment was investigated using the 125I-fibrinogen test. DVT was not significantly decreased by the ASL application (53%) compared to the controls (60%). DVT occurred significantly less under the combined administration (27%) than in the other two groups.
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Schöndorf et al. (2009) studied this question.
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