Why the study?
Does phosphorus-31 NMR spectroscopy reliably identify allograft rejection requiring augmented therapy in heart transplant patients?
Population
14 patients with heart transplants and 17 healthy control subjects.
Comparison
Image-guided, one-dimensional, phase-encoded… vs Healthy control subjects
Design
Cross-sectional
Authors
Loading...
NMR spectroscopy lacks accuracy to guide rejection therapy decisions; leaves open refinement of metabolic imaging for noninvasive surveillance in heart transplant patients.
Does phosphorus-31 NMR spectroscopy reliably identify allograft rejection requiring augmented therapy in heart transplant patients?
While phosphorus-31 NMR spectroscopy detects altered myocardial high-energy phosphate metabolism in heart transplant patients, it lacks the diagnostic accuracy to reliably identify clinically significant allograft rejection.
Bottomley et al. (1991) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: