Key result
Moderate physical activity significantly reduced all-cause mortality over 26 years in female coronary artery disease patients (HR 0.54), whereas smoking increased the risk (HR 1.56).
Why the study?
While behavioral factors predict CAD progression and outcomes within 3 to 5 years in women, whether they remain associated with all-cause mortality over 26 years was unknown.
Do behavioral factors predict long-term all-cause mortality in female coronary patients and healthy controls?
Population
292 female CAD patients and 300 healthy controls
Comparison
Behavioral, psychosocial, and cardiac risk profiles
Design
Prospective secondary analysis of a cohort study
Follow-up
Median 26 years
Authors
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May support lifestyle counseling in women with CAD; leaves open causality given the observational design.
Cohort (n=592)
Do behavioral factors predict long-term all-cause mortality in female coronary patients and healthy controls?
Hazard Ratio: 0.54 (95% CI 0.37–0.79)
p-value: p=0.002
Behavioral factors, specifically physical activity and smoking, are significant independent predictors of long-term all-cause mortality in women with coronary artery disease.
Deter et al. (2022) conducted a cohort in Coronary artery disease (n=592). Moderate physical activity vs. Sedentary lifestyle was evaluated on All-cause mortality (HR 0.54, 95% CI 0.37-0.79, p=0.002). Moderate physical activity significantly reduced all-cause mortality over 26 years in female coronary artery disease patients (HR 0.54), whereas smoking increased the risk (HR 1.56).
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