Why the study?
Does dexmedetomidine improve haemodynamic stability and reduce supplemental anaesthetic requirements compared to midazolam in patients undergoing elective off-pump coronary artery bypass surgery?
Population
107 patients scheduled for elective off-pump coronary artery bypass surgery (OPCAB)
Comparison
Dexmedetomidine as initial i.v. loading dose of… vs Midazolam 0.1 mg kg-1 over 1 min before…
Design
RCT, randomly allocated
Follow-up
until conclusion of surgery
Authors
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Favors dexmedetomidine over midazolam in off-pump CABG; extends RCT evidence for its adjunctive use in cardiac anaesthesia.
Does dexmedetomidine improve haemodynamic stability and reduce supplemental anaesthetic requirements compared to midazolam in patients undergoing elective off-pump coronary artery bypass surgery?
Dexmedetomidine is a more haemodynamically stable and potent anaesthetic adjunct than midazolam for patients undergoing off-pump coronary artery bypass surgery.
EmadEl-Din Mansour (2009) studied this question.
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