Why the study?
Does fish oil supplementation improve flow-mediated dilation in humans?
Population
16 randomized controlled trials pooling 1,385 human subjects
Comparison
Fish oil supplementation vs Control/placebo
Design
Meta-analysis
Authors
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High-quality double-blind trials show no endothelial benefit from fish oil; challenges overall meta-analysis and should not change practice.
Does fish oil supplementation improve flow-mediated dilation in humans?
While overall pooled data suggests fish oil improves endothelial function, high-quality double-blind placebo-controlled trials do not support a significant benefit.
Wei et al. (2012) studied this question.
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