Key result
Obesity was significantly associated with increased fasting blood sugar and altered lipid profiles in middle-aged women, with FBS levels of 151 mg/dL in overweight women compared to 90.73 mg/dL in normal-weight controls (p<0.001).
Why the study?
Type 2 diabetes is a major public health problem driven by risk factors including obesity and sedentary lifestyle, with its likelihood and severity closely linked to body mass index.
Does obesity worsen fasting blood sugar and lipid profiles in middle-aged women?
Cross-Sectional (n=110)
No
Does obesity worsen fasting blood sugar and lipid profiles in middle-aged women?
Absolute Event Rate: 151% vs 90.73%
p-value: p=<0.001
Obesity is significantly associated with adverse metabolic parameters, including elevated fasting blood sugar and atherogenic lipid profiles, in middle-aged women.
Obesity may signal higher cardiometabolic risk in middle-aged women; hypothesis-generating and requires prospective studies before practice change.
Background Type 2 diabetes is a serious and common chronic disease resulting from a complex inheritance-environment interaction along with other risk factors such as obesity and sedentary lifestyle. Type 2 diabetes and its complications constitute a major worldwide public health problem, affecting almost all populations in both developed and developing countries like India with high rates of diabetes-related morbidity and mortality. Materials & Method The study was conducted at Department of physiology, MNR Medical College & Hospital, Sangareddy, during the period of June 2017 to December 2017. 110 volunteer women of age 35 to 55 years were selected as subjects. The likelihood and severity of type 2 diabetes are closely linked with body mass index (BMI). Results There is a close association between obesity and type 2 diabetes. Comparison of mean values of various parameters in controls and group I. within group I, the mean values of FBS, HDL, TG & VLDL are higher with more significance (p<0.01). Conclusion The roles of genes, lifestyle and other factors contributing to rapid increase in the incidence of type 2 diabetes. The core aims are to bring forward the new therapy strategies and cost-effective intervention trials of type 2 diabetes.
No takes yet. Share an insight, caveat, or question.
A 2019 study conducted a cross-sectional in Obesity and Type 2 Diabetes Mellitus (n=110). Obesity (BMI ≥ 25 kg/m2) vs. Normal weight (BMI < 25 kg/m2) was evaluated on Fasting Blood Sugar (FBS) (p=<0.001). Obesity was significantly associated with increased fasting blood sugar and altered lipid profiles in middle-aged women, with FBS levels of 151 mg/dL in overweight women compared to 90.73 mg/dL in normal-weight controls (p<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: