Key result
A higher glucose-to-lymphocyte ratio was significantly associated with an increased risk of in-hospital mortality (HR 1.70) in patients with acute myocardial infarction.
Why the study?
GLR is associated with mortality in inflammatory diseases, but its association with in-hospital mortality and predictive value in AMI patients remained to be explored.
Does a high glucose-to-lymphocyte ratio predict increased in-hospital mortality in adult patients with acute myocardial infarction?
Population
Patients with AMI from the MIMIC-IV database (2012-2019)
Comparison
Higher GLR level vs lower GLR level
Design
Retrospective cohort study
Follow-up
In-hospital
Authors
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May flag high-risk AMI patients at the bedside but should not yet change practice; leaves open prospective tests of incremental value.
Cohort (n=1,805)
No
Does a high glucose-to-lymphocyte ratio predict increased in-hospital mortality in adult patients with acute myocardial infarction?
Hazard Ratio: 1.7 (95% CI 1.24–2.34)
Absolute Event Rate: 21.26% vs 6.21%
p-value: p=0.001
An elevated glucose-to-lymphocyte ratio at ICU admission is an independent predictor of in-hospital mortality in patients with acute myocardial infarction.
Liu et al. (2023) conducted a cohort in Acute myocardial infarction (n=1,805). High glucose-to-lymphocyte ratio (GLR > 106.14) vs. Low glucose-to-lymphocyte ratio (GLR ≤ 106.14) was evaluated on In-hospital mortality (HR 1.70, 95% CI 1.24-2.34, p=0.001). A higher glucose-to-lymphocyte ratio was significantly associated with an increased risk of in-hospital mortality (HR 1.70) in patients with acute myocardial infarction.
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