Key result
Stage 1 hypertension (130-139/80-89 mmHg) was associated with a significantly increased risk of incident cardiovascular disease compared to BP <120/<80 mmHg (HR 1.29; 95% CI 1.18-1.42).
Why the study?
To evaluate the associations of newly defined 2017 ACC/AHA blood pressure categories and blood pressure changes with cardiovascular disease risk in middle-aged and older Chinese adults.
Do newly defined blood pressure categories (2017 ACC/AHA guidelines) and long-term BP changes associate with incident cardiovascular disease in middle-aged and older Chinese adults?
Population
29 086 participants aged 61.6 years from the Dongfeng-Tongji cohort
Comparison
2017 ACC/AHA BP categories and BP changes vs normal or stable BP
Design
Cohort study
Follow-up
5-year period
Authors
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Supports 2017 ACC/AHA staging for CVD risk in Chinese adults; leaves open whether treating stage 1 hypertension reduces events.
Cohort (n=29,086)
Do newly defined blood pressure categories (2017 ACC/AHA guidelines) and long-term BP changes associate with incident cardiovascular disease in middle-aged and older Chinese adults?
Hazard Ratio: 1.29 (95% CI 1.18–1.42)
Newly defined stage 1 hypertension and elevated BP per the 2017 ACC/AHA guidelines are associated with a significantly increased risk of incident CVD, CHD, and stroke in middle-aged and older Chinese adults.
Ma et al. (2019) conducted a cohort in Cardiovascular disease (n=29,086). Stage 1 hypertension (BP 130-139/80-89 mmHg) vs. BP <120/<80 mmHg was evaluated on Incident cardiovascular disease (CVD) (HR 1.29, 95% CI 1.18-1.42). Stage 1 hypertension (130-139/80-89 mmHg) was associated with a significantly increased risk of incident cardiovascular disease compared to BP <120/<80 mmHg (HR 1.29; 95% CI 1.18-1.42).
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