Key result
The presence of a presystolic wave in asymptomatic hypertensive patients was associated with a significantly higher rate of subclinical left ventricular systolic dysfunction compared to its absence (31.6% vs 10%).
Why the study?
Presystolic waves are often found during LVOT Doppler evaluation in hypertensive individuals, with LV stiffness and altered compliance as potential mechanisms, but their association with subclinical LV impairment required evaluation.
Does the presence of a presystolic wave indicate subclinical left ventricular dysfunction in asymptomatic hypertensive patients?
Cross-Sectional (n=87)
Single-blind
No
Does the presence of a presystolic wave indicate subclinical left ventricular dysfunction in asymptomatic hypertensive patients?
The presence of a presystolic wave on Doppler echocardiography is associated with subclinical left ventricular systolic and diastolic dysfunction in asymptomatic hypertensive patients.
Answers are grounded in this paper and cite their sources.
Presystolic wave may flag subclinical LV systolic dysfunction in asymptomatic hypertension; hypothesis-generating pending prospective validation.
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Abdelkhalikk et al. (2024) conducted a cross-sectional in Essential hypertension (n=87). Presystolic wave vs. Absence of presystolic wave was evaluated on Subclinical LV systolic dysfunction (GLS < -19%) (p=0.025). The presence of a presystolic wave in asymptomatic hypertensive patients was associated with a significantly higher rate of subclinical left ventricular systolic dysfunction compared to its absence (31.6% vs 10%).
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