Key result
Higher morning home brachial systolic blood pressure was significantly associated with increased arterial stiffness (β = 0.06; 95% CI 0.01-0.11; P=0.02), whereas office-measured values were not.
Why the study?
Accurate blood pressure measurement is necessary to evaluate and treat hypertension to prevent the progression of subclinical vascular disease, including arterial stiffness.
Cross-Sectional (n=70)
Morning home brachial systolic blood pressure is more strongly associated with arterial stiffness than office-measured blood pressure in patients treated for hypertension.
Answers are grounded in this paper and cite their sources.
Should not yet change BP monitoring practice; leaves open whether morning home SBP is a better stiffness marker or treatment target.
Accurate blood pressure (BP) measurement is necessary for the evaluation and treatment of hypertension to prevent the progression of subclinical vascular disease, including arterial stiffness. We investigated the associations between brachial-ankle pulse wave velocity (baPWV), a measure of arterial stiffness, and each of office brachial systolic BP (SBP) with and without an observer present (attended or unattended office brachial SBP), attended or unattended office central SBP, and home brachial SBPs (specifically, the means of morning, evening, or morning-evening home brachial SBP) in patients being treated for hypertension. Measurements were performed among 70 adults (mean age, 67.0 ± 9.4 years; women, 51.4%) with a mean attended office brachial SBP of 127.6 ± 14.5 mmHg and mean baPWV of 16.3 ± 2.8 m/s. Univariate analysis showed that higher attended office brachial SBP, morning home brachial SBP, and morning-evening home brachial SBP were each statistically significantly associated with higher baPWV (r = 0.25, P = 0.04; r = 0.37, P = 0.002; and r = 0.32, P = 0.006, respectively). Multiple linear regression analysis with adjustments for traditional cardiovascular risk factors showed that only morning home brachial SBP was statistically significantly associated with baPWV [β = 0.06, 95% confidence interval (0.01-0.11), P = 0.02). In conclusion, higher morning home brachial SBP - but none of the office-measured SBP values - was associated with arterial stiffness.
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Mizuno et al. (2022) conducted a cross-sectional in Hypertension (n=70). Morning home brachial systolic blood pressure was evaluated on Arterial stiffness measured by brachial-ankle pulse wave velocity (baPWV) (β 0.06, 95% CI 0.01-0.11, p=0.02). Higher morning home brachial systolic blood pressure was significantly associated with increased arterial stiffness (β = 0.06; 95% CI 0.01-0.11; P=0.02), whereas office-measured values were not.
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