Acute Ischemic Vascular Events and Cisplatin

Letters and Corrections1 July 1987Acute Ischemic Vascular Events and CisplatinJAMES A. TALCOTT, M.D., TERENCE S. HERMAN, M.D.JAMES A. TALCOTT, M.D.Search for more papers by this author, TERENCE S. HERMAN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-107-1-121_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Doll and colleagues (1) recently reported acute ischemic vascular events after cisplatin-based chemotherapy in four young men with cancer of the testis. We report a case of myocardial infarction that occurred after radiation therapy and a different cisplatin-containing chemotherapy regimen in a young woman with lung cancer.A previously well 37-year-old nonsmoking women was hospitalized in March 1985, with a persistent cough. A medical evaluation showed bilateral supraclavicular adenopathy, a retrocardiac mass, and a lytic lesion in the L4 vertebral body. A supraclavicular lymph node biopsy specimen showed moderately well-differentiated squamous cell carcinoma consistent with a primary...References1. DOLLLISTGRECOHAINSWORTHHANDEJOHNSON DAFJKD. Acute vascular ischemic events after cisplatin-based combination chemotherapy for germ-cell tumors of the testis. Ann Intern Med. 1986;105:48-51. LinkGoogle Scholar2. HUFFSANDERS HE. Coronary artery occlusion after radiation. N Engl J Med. 1972;286:780. CrossrefMedlineGoogle Scholar3. SCHECHTERJONES JS. Myocardial infarction in a 27-year-old woman: possible complication of treatment with VP-16-213 (NSC-141540), mediastinal irradiation, or both. Cane Chemother Rep. 1975;59;887-8. MedlineGoogle Scholar4. BUCKNERRUDOLPHFEFER CRA. High-dose cyclophosphamide therapy for malignant disease: toxicity, tumor response, and the effects of stored autologous marrow. Cancer. 1972;29:357-65. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: The Dana-Farber Cancer Institute Joint Center for Radiation Therapy Boston, MA 02115 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByHypertension in Cancer Patients and SurvivorsCardiac Complications in the Adult Bone Marrow Transplant PatientCardiac and cardiovascular toxicity of nonanthracycline anticancer drugsVascular Toxicity of Antineoplastic AgentsCardiotoxicity of Cancer TherapyProspective evaluation of major vascular events in patients with nonsmall cell lung carcinoma treated with cisplatin and gemcitabineCardiotoxicity of Cancer ChemotherapyCardiotoxicity of Chemotherapeutic AgentsAcute Coronary Events Following Cisplatin-Based Chemotherapy 1 July 1987Volume 107, Issue 1Page: 121-122KeywordsBiopsyChemotherapyLesionsLung and intrathoracic tumorsLymph nodesMyocardial infarctionRadiation therapySquamous cell carcinomaTesticular cancer Issue Published: 1 July 1987 PDF DownloadLoading ...