September 30, 2016Biomedical ReportsOpen Access

G2691A and C2491T mutations of factor V gene and pre-disposition to myocardial infarction in Morocco

View Full Paper

Ask AI

Bookmark

Why the study?

Does the C2491T non-sense mutation of the factor V gene increase the risk of myocardial infarction in a Moroccan population?

Structured PICO

Does the C2491T non-sense mutation of the factor V gene increase the risk of myocardial infarction in a Moroccan population?

Population

311 subjects, including 100 patients with myocardial infarction (MI) ≤3 years ago and 211 healthy control subjects from volunteer blood donors with no history of MI, recruited in Casablanca, Morocco.

Intervention

Presence of the C2491T non-sense mutation and G2691A (Factor V Leiden) mutation in the factor V gene

Comparator

Absence of the mutations (wild-type genotypes)

Outcome

Risk of developing myocardial infarctionhard clinical

The C2491T non-sense mutation of the factor V gene is significantly associated with an increased risk of myocardial infarction in the Moroccan population.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Does not support routine testing yet; leaves open replication in prospective cohorts before risk stratification use.

Cite This Study

Hmimech et al. (2016) studied this question.

synapsesocial.com/papers/6a7f5c175685e30b766f7efc https://doi.org/10.3892/br.2016.768

View Full Paper

Ask AI

Bookmark

G2691A and C2491T mutations of factor V gene and pre-disposition to myocardial infarction in Morocco

Structured PICO

Discussion

Implication

Cite This Study

G2691A and C2491T mutations of factor V gene and pre-disposition to myocardial infarction in Morocco

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider