Why the study?
Does preoperative serum PN concentration predict mortality in patients with early breast cancer receiving curative surgery?
Population
182 patients with early breast cancer (BCa) receiving curative surgery
Design
Cohort
Authors
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Subgroup associations in node-negative/low-PgR early breast cancer are hypothesis-generating; prospective validation needed before any clinical use.
Does preoperative serum PN concentration predict mortality in patients with early breast cancer receiving curative surgery?
Preoperative serum periostin levels may predict worse long-term survival in specific subgroups of early breast cancer patients, such as those with node-negative disease or low PgR expression.
Nuzzo et al. (2015) studied this question.
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