This review highlights the critical prognostic role of the coronary microcirculation in STEMI and discusses invasive and non-invasive methods for its assessment and potential therapeutic strategies.
Microcirculatory assessment may refine STEMI management beyond PPCI; leaves open whether catheter-based techniques improve outcomes in prospective trials.
Coronary microcirculation plays a crucial role for the outcomes of patients with STEMI. Although PPCI improves outcomes compared to thrombolysis, a substantial amount of STEMI patients do not achieve optimal myocardial reperfusion. Angiographic methods for assessment of reperfusion like TIMI Flow and MBG are easy to use but new, catheter laboratory based techniques to assess reperfusion have a lot of potential to assess and potentially guide management of patients with STEMI.
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Kharbanda et al. (2011) studied this question.
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