June 15, 2011Clinical Endocrinology
Salivary chromogranin A, but not α-amylase, correlates with cardiovascular parameters during high-intensity exercise
Why the study?
Does salivary chromogranin A correlate with cardiovascular parameters during high-intensity exercise in healthy men?
Population
21 healthy men
Comparison
Standardized treadmill stress test vs Baseline (before exercise)
Design
Cross-sectional
Follow-up
30 minutes during recovery phase
Authors
Discussion
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Member takes
Overview
sCgA correlations with exercise hemodynamics may reflect sympathoadrenal activity; leaves open biomarker utility pending prospective validation.
Structured PICO
Does salivary chromogranin A correlate with cardiovascular parameters during high-intensity exercise in healthy men?
P
Population
21 healthy men
I
Intervention
Standardized treadmill stress test (high-intensity exercise)
C
Comparator
Baseline (before exercise)
O
Outcome
Levels of salivary chromogranin A (sCgA) and alpha-amylase (sAA) and their correlation with cardiovascular parameters (double product of blood pressure and heart rate) and perceived exertionsurrogate
Salivary chromogranin A is a reliable noninvasive marker of sympathoadrenal medullary activation that correlates with cardiovascular parameters during high-intensity exercise.
Cite This Study
Gallina et al. (2011) studied this question.