Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 1, 1989The Journal of Infectious Diseases

Epidemiology of Otitis Media During the First Seven Years of Life in Children in Greater Boston: A Prospective, Cohort Study

View Full Paper
Ask AI
Bookmark
Share

Authors

DTDavid W. TeeleArrow International (United States)JKJerome O. KleinRonald Reagan UCLA Medical CenterBRBernard RosnerBrigham and Women's Hospital

Discussion

Loading...

Member takes

Implication

Prospective cohort study reveals high incidence of acute otitis media and effusion in young children, highlighting risks from lack of breastfeeding and family history.

Key Points

  • To determine the epidemiology, incidence, and risk factors of acute otitis media (AOM) and the duration of middle ear effusion (MEE) from birth through seven years of age.
  • Prospective cohort study tracking consecutively enrolled infants from shortly after birth up to 7 years of age.
  • Evaluated cohorts of children followed for at least 1 year (N=877), at least 3 years (N=698), and through 7 years (N=498).
  • Applied multivariate analysis to identify independent risk factors associated with AOM occurrence and MEE duration.
  • By 1 year of age, 62% of children experienced ≥1 episode of AOM and 17% had ≥3 episodes; by 3 years, 83% had ≥1 episode and 46% had ≥3 episodes, peaking between 6 and 12 months of age.
  • Multivariate analysis showed significantly increased risk of AOM associated with male sex, sibling history of recurrent AOM, early first occurrence of AOM, and not being breastfed.
  • Middle ear effusion persisted for weeks to months post-AOM, with prolonged duration significantly associated with male sex, sibling history of ear infection, and lack of breastfeeding.

Cite This Study

Teele et al. (1989) studied this question.

synapsesocial.com/papers/6a7f81890d0db10a3890780ehttps://doi.org/10.1093/infdis/160.1.83
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Otitis Media Among Children in Day Care: Epidemiology and Pathogenesis1986 · 48 citations
  2. 2Penicillin and Acute Otitis1980 · 33 citations