Why the study?
Does alcohol dependence severity correlate with altered fronto-striatal functional connectivity during response inhibition?
Population
20 individuals with alcohol dependence who were prospectively genotyped on the OPRM1 gene
Design
Cross-sectional
Authors
Loading...
Does not support practice changes in alcohol use disorder; leaves open causal links between dependence severity and fronto-striatal connectivity.
Does alcohol dependence severity correlate with altered fronto-striatal functional connectivity during response inhibition?
More severe alcohol dependence is associated with weakened fronto-striatal functional connectivity during response inhibition, suggesting progressive impairment of cognitive control networks.
Courtney et al. (2012) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: