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The objective of this study is to identify potential targets within the SARS-CoV-2 RdRp for the discovery of novel inhibitors derived from therapeutic natural compounds sourced from aromatic and medicinal plants. In the course of this study, a library was generated containing five naturally occurring flavone derivatives (4a, 4b, 4c, 4d, and 4e) in conjunction with the standard favipiravir-RTP. The compounds underwent an in-silico methodology involving critical steps, including (a) evaluating ADM
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Merzouki et al. (2023) studied this question.
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