Population
Frog single muscle fibres
Comparison
Active shortening during twitch and tetanus vs Passive shortening or control (no shortening)
Design
Preclinical
Authors
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May influence sarcomere models in cardiac research; leaves open relevance to mammalian myocardium or clinical practice.
Active shortening of frog muscle fibers depresses contractile force, likely due to reduced binding of activator calcium to regulatory proteins.
K. A. P. Edman (1980) studied this question.
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