Why the study?
Metabolic reprogramming plays a critical role in pulmonary arterial hypertension pathogenesis, and understanding mitochondrial metabolic mechanisms could provide viable therapeutic approaches.
Design
Review
Authors
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Mitochondrial pathway modulation should not yet change PAH practice; leaves open whether it extends current vasodilator strategies.
Understanding mitochondrial metabolic mechanisms in PAH could provide viable therapeutic approaches for patients.
Liang et al. (2022) studied this question.
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