Why the study?
Current heart failure treatments incompletely address unmet clinical needs, and splanchnic nerve block confers potential adverse effects and complications warranting further investigation.
Does splanchnic nerve block improve hemodynamic parameters in patients with heart failure?
Does splanchnic nerve block improve hemodynamic parameters in patients with heart failure?
Splanchnic nerve block is an emerging therapeutic strategy for heart failure that may improve hemodynamics but requires further investigation into its safety profile.
Splanchnic nerve block may improve hemodynamics in acute and chronic HF; leaves open safety, durability, and efficacy for randomized trials.
Heart failure (HF) is a disease syndrome whose management is increasingly challenging given the aging population and efficacious management of acute cardiac events. The current treatment options within our armamentarium incompletely address the unmet needs of HF. Splanchnic nerve block (SNB) is a novel technique that targets the greater splanchnic nerve, a potential therapeutic target in HF. However, the technique confers potential adverse side effects and complications that warrant further investigations. In this review paper, we aim to discuss the inextricable role of splanchnic nerve in HF by highlighting their physiological interplay, clinical studies that have exhibited favorable hemodynamic parameters in the context of acute and chronic HF, and common side effects and possible complications from SNB.
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Tung et al. (2022) studied this question.
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