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March 1, 2009Coronary Artery Disease

B-type natriuretic peptide: a strong predictor of early and late mortality in patients with acute chest pain without ST-segment elevation in the emergency department

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Why the study?

Does admission BNP level predict early and late cardiac mortality in patients with acute chest pain without ST-segment elevation?

Population

723 consecutive individuals with suspicious ischemic acute chest pain and no ST-segment elevation presenting…

Comparison

Admission B-type natriuretic peptide measurement vs BNP ≤101 pg/ml

Design

Cohort

Follow-up

1 year

Authors

RBRoberto BassanBTBernardo Rangel TuraAMAlan S. Maisel

Discussion

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Overview

Admission BNP may stratify mortality risk in non-ST-elevation chest pain; hypothesis-generating for prospective validation before clinical use.

Structured PICO

Does admission BNP level predict early and late cardiac mortality in patients with acute chest pain without ST-segment elevation?

P
Population
723 consecutive individuals with suspicious ischemic acute chest pain and no ST-segment elevation presenting to the emergency department
I
Intervention
Admission B-type natriuretic peptide (BNP) measurement (specifically >101 pg/ml)
C
Comparator
BNP ≤101 pg/ml
O
Outcome
Cardiac mortality at 1 month and 1 yearhard clinical

Admission BNP is a strong independent predictor of 1-month and 1-year cardiac mortality in patients presenting to the emergency department with acute chest pain without ST-segment elevation.

Cite This Study

Bassan et al. (2009) studied this question.

synapsesocial.com/papers/6a7fd9b6cab4e68c85153167https://doi.org/10.1097/mca.0b013e3283292ac6
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Also Consider

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  4. 4Comparing the Areas under Two or More Correlated Receiver Operating Characteristic Curves: A Nonparametric Approach1988 · 23,064 citations
  5. 5N-Terminal Pro–B-Type Natriuretic Peptide Levels for Dynamic Risk Stratification of Patients With Acute Coronary Syndromes2004 · 282 citations