Why the study?
How do cardiac index, stroke index, and left ventricular ejection fraction change with age at rest and during exercise in healthy subjects?
Population
148 healthy subjects, age range 6-78 years
Design
Cross-sectional
Authors
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Observed age-related declines in resting cardiac index, stroke index, and LVEF; hypothesis-generating for exercise responses and prognostic value.
How do cardiac index, stroke index, and left ventricular ejection fraction change with age at rest and during exercise in healthy subjects?
Cardiac index, stroke index, and left ventricular ejection fraction decline progressively with age at rest, with blunted exercise responses in older individuals.
Kuikka et al. (1982) studied this question.