September 12, 2023International Heart JournalOpen Access

Rhythm of Acute Aortic Syndrome in Northeastern China

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Why the study?

To improve predictability and prevention of acute aortic syndromes by investigating daily, weekly, monthly, and seasonal variations in onset.

Population

1,197 patients treated for AAS in Liaoning Province, Northeast China

Comparison

Timing and rhythmicity of AAS onset across daily, weekly, monthly, and seasonal periods

Design

Retrospective observational study

Authors

LYLin YangChinese Academy of Medical Sciences & Peking Union Medical College YWYasong WangGeneral Hospital of Shenyang Military Region XLXuanze LiuChina National Nuclear Corporation

Discussion

Member takes

Implication

Should not yet alter AAS prevention or staffing; leaves open generalizability and whether temperature effects are causal.

Structured PICO

Population

1,197 patients treated for acute aortic syndromes (AAS) at a single center in Liaoning Province, Northeast China, between June 2002 and June 2021. Mean age 54.9 years, 75.6% male. Key inclusion: first occurrence of AAS (acute AD, acute IMH, acute PAU) defined by an interval of ≤14 days between onset and arrival. Key exclusion: chronic aortic syndrome, traumatic AD, iatrogenic AD, aortic aneurysm, Marfan's syndrome.

Outcome

Daily, weekly, monthly, and seasonal variations in the onset of acute aortic syndromes

Acute aortic syndromes in Northeast China exhibit significant circadian and seasonal rhythms, peaking in the afternoon and during colder months, which may inform targeted preventive strategies.

Limitations

Retrospective observational study with inherent shortcomings
Data collected from electronic medical records, part of which was based on patients' and their relatives' recall, leading to potential inclusion bias
Single-center study, results may not apply to other climate regions and nations

Cite This Study

Yang et al. (2023) studied this question.

synapsesocial.com/papers/6a7fea0a5b3c71e5ca502983 https://doi.org/10.1536/ihj.23-028

Topics

Hypertension management

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Rhythm of Acute Aortic Syndrome in Northeastern China

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Topics

Rhythm of Acute Aortic Syndrome in Northeastern China

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Topics

Also Consider