Why the study?
Initial presentation of systemic lupus erythematosus as decompensated dilated cardiomyopathy is exceedingly rare, with a paucity of clinical evidence and consensus regarding therapeutic approaches.
Does high-dose steroid therapy improve clinical and functional recovery in patients with SLE presenting as dilated cardiomyopathy with acute heart failure?
Does high-dose steroid therapy improve clinical and functional recovery in patients with SLE presenting as dilated cardiomyopathy with acute heart failure?
High-dose steroid therapy appears effective for clinical and functional recovery in the rare presentation of SLE as acute decompensated dilated cardiomyopathy, based on limited case reports.
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May warrant SLE serologies in unexplained decompensated DCM lacking typical risks; leaves open first-line steroids given only case-level data.
Durrance et al. (2019) studied this question.
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