In patients with first-ever minor stroke, multiple lacunar infarcts are independently predicted by CT leukoaraiosis, cardiomegaly, and higher admission diastolic blood pressure, suggesting a specific hypertensive arteriolosclerosis pathology.
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Highlights potential markers for lacunar multiplicity in minor stroke; hypothesis-generating and requires prospective validation before clinical use.
Spolveri et al. (1998) studied this question.
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