Key result
Fixed-dose beta-blocker plus ACE inhibitor lowers BP and heart rate, improving CAD outcomes.
Open surgical repair of thoracic aortic false aneurysms is associated with high in-hospital mortality (6-41%) but provides acceptable long-term survival (68% at 10 years) for patients with this life-threatening condition.
May support fixed beta blocker/ACE inhibitor combinations in hypertensive CAD; leaves open confirmation of prognostic benefit in randomized trials.
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Ondřej Petrák (2024) conducted a review in Arterial hypertension and coronary artery disease. Beta blocker (bisoprolol) and ACE inhibitor (perindopril) combination was evaluated. The fixed combination of a beta blocker and an ACE inhibitor effectively lowers blood pressure and heart rate, improving cardiovascular prognosis in patients with hypertension and coronary artery disease.
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