July 1, 2010Archives of General Psychiatry
Scared to Death? Generalized Anxiety Disorder and Cardiovascular Events in Patients With Stable Coronary Heart Disease
Why the study?
Does generalized anxiety disorder increase the risk of cardiovascular events in outpatients with stable coronary heart disease?
Population
1,015 outpatients with stable coronary heart disease from 12 outpatient clinics in the San Francisco Bay Area.
Comparison
Presence of generalized anxiety disorder… vs Absence of generalized anxiety disorder (n=909).
Design
Cohort
Follow-up
mean 5.6 years
Authors
Discussion
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Member takes
Implication
GAD may warrant screening in stable CHD; leaves open whether anxiety treatment reduces events.
Structured PICO
Does generalized anxiety disorder increase the risk of cardiovascular events in outpatients with stable coronary heart disease?
P
Population
1,015 outpatients with stable coronary heart disease (CHD) from 12 outpatient clinics in the San Francisco Bay Area.
I
Intervention
Presence of generalized anxiety disorder (GAD) determined using the Diagnostic Interview Schedule (n=106).
C
Comparator
Absence of generalized anxiety disorder (n=909).
O
Outcome
Subsequent cardiovascular events.composite
Generalized anxiety disorder is independently associated with a significantly increased risk of subsequent cardiovascular events in patients with stable coronary heart disease.
Cite This Study
Martens et al. (2010) studied this question.