Why the study?
Do invasive treatments (dual-chamber pacing, surgical myectomy, alcohol septal ablation) effectively reduce left ventricle outflow tract gradient in patients with drug-refractory obstructive hypertrophic cardiomyopathy?
Population
194 patients with hypertrophic cardiomyopathy.
Comparison
Invasive treatments for obstructive HCM… vs Treatments were compared across different…
Design
Cohort
Authors
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Supports gradient reduction with these methods in obstructive HCM; leaves open need for randomized outcome comparisons.
Do invasive treatments (dual-chamber pacing, surgical myectomy, alcohol septal ablation) effectively reduce left ventricle outflow tract gradient in patients with drug-refractory obstructive hypertrophic cardiomyopathy?
Surgical myectomy, dual-chamber pacing, and alcohol septal ablation are all effective in reducing LVOT obstruction in appropriately selected patients with drug-refractory hypertrophic cardiomyopathy.
Knyshov et al. (2012) studied this question.
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