Population
Rodents with either swimming-induced mild myocardial hypertrophy or pathologic heart hypertrophy related to…
Design
Preclinical
Authors
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May differentiate physiological from pathological hypertrophy via prostanoids in rodents; hypothesis-generating for human exercise or hypertension studies.
Physiological hypertrophy from exercise increases cardioprotective prostanoids, whereas pathological hypertrophy from hypertension reduces them, suggesting a potential benefit of linoleic acid supplementation during intense physical training.
Khrushchev et al. (1993) studied this question.
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