Role of multidetector computed tomography in the diagnosis and management of patients attending the rapid access chest pain clinic, The Scottish computed tomography of the heart (SCOT-HEART) trial: study protocol for randomized controlled trial
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Why the study?
Does the addition of CT coronary angiography and calcium scoring to standard care improve the diagnosis of angina pectoris secondary to coronary heart disease in patients attending a rapid access chest pain clinic?
Population
4,138 patients attending the rapid access chest pain clinic for evaluation of suspected cardiac chest pain…
Comparison
Standard care plus ≥64-multidetector computed… vs Standard care alone (no additional scanning).
Design
RCT, 1:1 randomization using a web-based system to ensure allocation…
Follow-up
6 weeks (primary endpoint), 6 months, and long-term
Authors
Discussion
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Implication
The SCOT-HEART trial protocol outlines a large randomized study to evaluate whether adding CT coronary angiography to standard care improves the diagnosis and management of patients presenting with suspected cardiac chest pain.
Structured PICO
Does the addition of CT coronary angiography and calcium scoring to standard care improve the diagnosis of angina pectoris secondary to coronary heart disease in patients attending a rapid access chest pain clinic?
P
Population
4,138 patients attending the rapid access chest pain clinic for evaluation of suspected cardiac chest pain, age >18 and ≤75 years. Key exclusions: inability to undergo CT, severe renal failure (eGFR <30 ml/min), major allergy to iodinated contrast, acute coronary syndrome within 3 months.
I
Intervention
Standard care plus ≥64-multidetector computed tomography (CT) coronary angiography and coronary calcium score within 14 days of clinic attendance.
C
Comparator
Standard care alone (no additional scanning).
O
Outcome
Proportion of patients diagnosed with angina pectoris secondary to coronary heart disease at 6 weeks.
The SCOT-HEART trial protocol outlines a large randomized study to evaluate whether adding CT coronary angiography to standard care improves the diagnosis and management of patients presenting with suspected cardiac chest pain.
Cite This Study
Newby et al. (2012) studied this question.
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